Thrombotic microangiopathy related to anticardiolipin antibody in a renal allograft
نویسندگان
چکیده
منابع مشابه
Renal thrombotic microangiopathy associated with anticardiolipin antibodies in hepatitis C-positive renal allograft recipients.
Hepatitis C virus (HCV) infection has been associated with de novo or recurrent membranoproliferative glomerulonephritis and acute transplant glomerulopathy in transplanted kidneys. Recently, anticardiolipin antibodies (ACA) have been linked with chronic HCV infection. A few reports have suggested an association between ACA and renal allograft thrombosis. This study examines the clinical and pa...
متن کاملThrombotic Microangiopathy in Renal Allografts
The term “thrombotic microangiopathy” (TMA) encompasses non-inflammatory small vessel vasculopathies that are caused by severe endothelial and medial smooth muscle cell injury/necrosis. TMAs can be promoted by a variety of “toxic” stimuli ranging from malignant range hypertension, E. coli infections with bloody diarrhea, radiation, systemic diseases such as scleroderma to iatrogenic events such...
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After kidney transplantation, thrombotic microangiopathy (TMA) can occur de novo or as recurrent disease. Risk factors for de novo posttransplant TMA include ischemia-reperfusion injury, immunosuppressive drugs, viral infections, acute humoral rejection, and complement gene abnormalities. Cytomegalovirus infection as a trigger for posttransplant TMA in kidney transplant recipients has only been...
متن کاملDe novo thrombotic microangiopathy induced by cytomegalovirus infection leading to renal allograft loss.
After kidney transplantation, thrombotic microangiopathy (TMA) can occur de novo or as recurrent disease. Risk factors for de novo posttransplant TMA include ischemia-reperfusion injury, immunosuppressive drugs, viral infections, acute humoral rejection, and complement gene abnormalities. Cytomegalovirus infection as a trigger for posttransplant TMA in kidney transplant recipients has only been...
متن کاملCyclosporine-associated thrombotic microangiopathy in renal allografts.
BACKGROUND The association between cyclosporine (CsA) and thrombotic microangiopathy (TMA) in renal allografts is well documented. However, predisposing factors and therapy guidelines are not adequately characterized. METHODS We reviewed 188 patients with kidney or kidney-pancreas transplants who were treated between January 1994 and December 1996 with prednisone, CsA, or tacrolimus, and azat...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 1999
ISSN: 1460-2385
DOI: 10.1093/ndt/14.2.436